Melilot was born in TA 2985 (SR 1385) and was the youngest child of Marmadas Brandybuck. Melilot's siblings were called Merimas and Mentha. She was a guest at the farewell party of Bilbo Baggins. At Bilbo's 111th birthday party on September 22, 3001, Melilot Brandybuck and Everard Took began to dance the Springle-ring on a table when they mistakenly thought Bilbo's speech was over. She was a third cousin of Meriadoc Brandybuck.